POCKET AIR® LoyalCare
LoyalCare Nebulization System Product Image

Inline Aerosol Drug Delivery Solution

The world's first Polyimide (PI)-based closed aerosol drug delivery platform. Specially engineered for patients requiring mechanical ventilators or other positive pressure/high-flow respiratory support circuits, its expanded mist reservoir design significantly enhances lung deposition rates.

LoyalCare Airflow Animation
LoyalCare
SVN/pMDI Airflow Animation
SVN/pMDI

POLYIMIDE (PI) Advantages

During nebulization, aerosol particles are highly susceptible to electrostatic attraction, causing them to adhere to metal surfaces. Utilizing PI material minimizes static generation and reduces drug residue on circuit surfaces, thereby maximizing aerosol output and inhalation efficiency.

PI Material Surface Comparison
PI Material
Metal Material Surface Comparison
Metal Material
 
01

Shear Stress Control

Polyimide (PI) undergoes elastic deformation under fluid pressure, mitigating abrupt flow velocity changes and reducing shear rates. Unlike rigid metals, it prevents damage caused by amplified instantaneous stress.

 
02

Thermal Damage Prevention

PI’s low thermal conductivity ensures that heat does not accumulate on the working surface. This prevents localized hot spots, significantly reducing the risk of damaging sensitive bio-substances.

 
03

Reduced Surface Adsorption

With higher hydrophobicity than metals, PI minimizes protein and lipid adsorption, thereby inhibiting the degradation caused by interfacial shear stress.

 
04

Superior Chemical Stability

PI is chemically inert and non-metallic. It does not release metal ions during nebulization, ensuring that the properties of biological molecules or liposomes remain intact.

 
05

Advanced Micro-machining

The high processability of PI allows for the fabrication of precise microporous structures, ensuring product consistency and exceptional performance for high-accuracy nebulization needs.

Versatile Respiratory Therapy Support

Literature Reference

LoyalCare Connection Diagram 

Invasive Icon

Invasive Mechanical Ventilation

Effectively delivers aerosolized medications to patients during Invasive Mechanical Ventilation (IMV).

NGI (Next Generation Impactor) In-Vitro Performance Data

Bronchodilator
Salbutamol (Ventolin)
MMAD: 3.916
GSD: 1.803
FPF(<5μm): 66.59%
FPF(<3.3μm): 37.69%
Bronchodilator
Terbutaline (Bricanyl)
MMAD: 3.879
GSD: 1.825
FPF(<5μm): 66.33%
FPF(<3.3μm): 38.43%
Antibiotic
Colistin (Colimycin)
MMAD: 3.249
GSD: 1.858
FPF(<5μm): 75.66%
FPF(<3.3μm): 50.71%
*Performance data derived from in-vitro product testing at MicroBase Analytical Laboratory.
IMV Scenario
Non-invasive Icon

Non-Invasive Ventilation

Directly compatible with CPAP (Continuous Positive Airway Pressure) and BiPAP (Bilevel Positive Airway Pressure). Can be integrated without supplementary flow or interrupting the therapy cycle.

NIV Scenario
High-flow Icon

High-Flow

Allows in-line drug administration without treatment interruption. Maintaining a closed respiratory circuit effectively reduces infection risks and improves therapeutic efficiency.

NGI (Next Generation Impactor) Performance Data

Flow Rate 40 L/min
Ipratropium (Atrovent)
MMAD: 2.62
GSD: 1.479
FPF(<5μm): 75.23%
FPF(<3.3μm): 56.79%
Flow Rate 50 L/min
Ipratropium (Atrovent)
MMAD: 2.511
GSD: 1.436
FPF(<5μm): 60.18%
FPF(<3.3μm): 48.01%
*Performance data derived from in-vitro product testing at MicroBase Analytical Laboratory.
High-flow Scenario

Field and Medical-Grade Design

USB Controller

USB Controller Product
  • USB-compatible for power bank usage in field operations.
  • Automatically power off within 30 minutes.
  • Dual mounting options for various hospital settings.
  • Standby indicator for clear shift handover without re-confirmation.

T-Piece

T-Piece Product
  • PP material, heat-resistant and BPA-free for patient safety.
  • Spherical T-Piece increases the amount of drugs directly to the lungs.
  • Compatible with humidifier and heater for comfort and absorption.
  • Can be connected by accessories meets ISO 5356 standard.

Elevating Clinical Care

ICU / Long-Term Care Facilities
  • Single patient use.
  • Using time: 28 days (4 treatments per day).
  • Intended user : Neonates (29 days or older) and adult patients.
ICU Clinical Context

Protecting Healthcare Workers’Safety

The closed-circuit design minimizes the risk of exposure to pathogens.

Precise Drug Delivery Control

Effective drug utilization through low residue and high inhalation efficiency.

Reducing Healthcare Burden

Compared to metered-dose inhalers (MDIs), ICU length of stay is reduced by 28%. Compared to jet nebulizers, exposure is reduced by 14%.¹

1. Source: CADTH Health Technology Review (2021)

Streamlined Operation

Step 1

Connect the AC/DC power adapter to the power outlet.

Step 2

Connect the USB controller to the power adapter.

Step 3

③ Check the blue light on the USB controller is on.

Step 4

Plug the nebulizer cable to the nebulizer.

Model MB05T01
Method of operation Active Vibrating Mesh Technology
Power Supply AC/DC Adapter:
- Please use a power adapter that meets the requirements of IEC60601-1 and CCC certification standards.
- Specification: 5V DC, 1A
Vibration Freq. Approx. 120 (kHz) ±10%
Nebulization Rate ≥ 0.2 mL / min
Particle Size MMAD ≤ 5μm
Capacity of Nebulizer Maximum 6 mL
Intended user 29 days Neonatal or older and adult.
Operator must be legally practicing medical personnel.
Operating Env. Temp: 10°C - 40°C; RH: 30 - 85%; Pressure: 800 - 1060hPa
Storage Env. Temp: -20 - 70°C; RH: 20 - 75%; Pressure: 800 - 1060hPa
Service Life 28 days (4 treatments per day).
Weight USB Controller: Approx. 100g
Medication Cup: Approx. 6.5g
Kit Contents USB Controller, T-Piece, Nebulizer and Adapter.